A <i>Cutibacterium acnes</i> antibiotic modulates human skin microbiota composition in hair follicles
Jan Claesen, Jennifer Spagnolo, Stephany Flores Ramos, Kenji L. Kurita, Allyson L. Byrd, Alexander A. Aksenov, Alexey V. Melnik, Weng Ruh Wong, Shuo Wang, Ryan D. Hernandez, Mohamed S. Donia, Pieter C. Dorrestein, Heidi H. Kong, Julia A. Segre, Roger G. Linington, Michael A. Fischbach, Katherine P. Lemon
Abstract
Cutimycin, a thiopeptide antibiotic produced by the skin commensal Cutibacterium acnes , reduces Staphylococcus colonization of human skin hair follicles.
Topics & Concepts
AntibioticsHuman skinHair follicleColonizationMicrobiologyStaphylococcus aureusBiologyMicrobiomeBacteriaCell biologyBioinformaticsGeneticsDermatology and Skin DiseasesAcne and Rosacea Treatments and EffectsHair Growth and Disorders