E3 ligase SCFSKP2 ubiquitinates and degrades tumor suppressor C/EBPα in acute myeloid leukemia
Gatha Thacker, Mukul Mishra, Akshay Sharma, Anil Singh, Sabyasachi Sanyal, Arun Kumar Trivedi
Topics & Concepts
Myeloid leukemiaUbiquitin ligaseCcaat-enhancer-binding proteinsBiologySKP2Cancer researchMolecular biologyMyeloidUbiquitinEctopic expressionTransactivationCell biologyChemistryNuclear proteinTranscription factorCell cultureBiochemistryGeneticsGeneAcute Myeloid Leukemia ResearchUbiquitin and proteasome pathwaysProtein Degradation and Inhibitors