Enhanced in vitro cytotoxicity and antitumor activity in vivo of iridium(III) complexes liposomes targeting endoplasmic reticulum and mitochondria
Wenlong Li, Xiaoyu Wu, Haimei Liu, Chuanling Shi, Yuhan Yuan, Lan Bai, Xiaofei Liao, Yuanyuan Zhang, Yunjun Liu
Topics & Concepts
HeLaChemistryApoptosisIn vivoCytotoxic T cellCytotoxicityEndoplasmic reticulumIn vitroCancer cellA549 cellMolecular biologyPharmacologyCell biologyBiochemistryCancerBiologyBiotechnologyGeneticsMetal complexes synthesis and propertiesSynthesis and Characterization of Heterocyclic CompoundsCancer therapeutics and mechanisms