Asymmetric addition of hydrazones as alkyl carbanion equivalents with aryl imines in water
Yizhan Wang, Shao-Dong Liu, Liang Cheng, Li Liu, Chao‐Jun Li
Abstract
An asymmetric umpolung addition of hydrazones as alkyl carbanion equivalents with imines in water was developed under the catalysis of a chiral Ru–diamine–diphosphine system.
Topics & Concepts
CarbanionChemistryUmpolungAlkylArylEquivalentMedicinal chemistryCatalysisOrganic chemistryNucleophileBiochemistryAsymmetric Hydrogenation and CatalysisN-Heterocyclic Carbenes in Organic and Inorganic ChemistryCoordination Chemistry and Organometallics