Borreliella burgdorferi Antimicrobial-Tolerant Persistence in Lyme Disease and Posttreatment Lyme Disease Syndromes
Felipe C. Cabello, Monica E. Embers, Stuart A. Newman, Henry P. Godfrey
Abstract
The annual incidence of Lyme disease, caused by tick-transmitted Borreliella burgdorferi , is estimated to be at least 476,000 cases in the United States and many more worldwide. Ten to 20% of antimicrobial-treated Lyme disease patients display posttreatment Lyme disease syndrome (PTLDS), a clinical complication whose etiology and pathogenesis remain uncertain.
Topics & Concepts
Lyme diseaseBorrelia burgdorferiPersistence (discontinuity)DiseaseMedicineAntimicrobialVirologyBiologyMicrobiologyImmunologyPathologyEngineeringAntibodyGeotechnical engineeringVector-borne infectious diseasesMosquito-borne diseases and controlViral Infections and Vectors