Litcius/Paper detail

Acute ANCA Vasculitis and Asymptomatic COVID-19

Weston T. Powell, Julie A. Campbell, Francesca Ross, Patricia Peña Jiménez, Erin R. Rudzinski, Jane A. Dickerson

2021PEDIATRICS65 citationsDOIOpen Access PDF

Abstract

We describe the presentation and diagnosis of a child with newly diagnosed antineutrophil cytoplasmic antibody-associated vasculitis and associated diffuse alveolar hemorrhage who was positive for coronavirus disease 2019 immunoglobulin G antibodies, indicative of a previous asymptomatic infection. Results of multiple polymerase chain reaction tests coinciding with the start of symptoms were negative, indicating that acute infection was not the cause of the patient's symptoms. Coronavirus disease 2019-induced autoimmune diseases have been described in adults, but this case report represents the first case described in a pediatric patient.

Topics & Concepts

MedicineAsymptomaticCoronavirus disease 2019 (COVID-19)Vasculitis2019-20 coronavirus outbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)ANCA-Associated VasculitisVirologyDermatologyPathologyInfectious disease (medical specialty)OutbreakDiseaseVasculitis and related conditionsCOVID-19 Clinical Research StudiesDermatological and COVID-19 studies