Examining recruitment feasibility and related outcomes in adults post-stroke
Erin King, Megan Doherty, Daniel M. Corcos, Mary Ellen Stoykov
Abstract
BACKGROUND: There are limited effective and evidence-based interventions for upper extremity hemiparesis post-stroke. To prepare for an RCT and minimize misuse of resources, there is value in conducting a feasibility study. OBJECTIVE: To examine the feasibility of recruitment and other related outcomes for an intense upper limb intervention. METHODOLOGY: Feasibility outcomes included retention, adherence, accrual rate, sample characteristics, and identification of productive recruitment methods. Other outcomes included satisfaction with the study, fidelity, and equipoise of both staff and participants. RESULTS: Participants were enrolled at a rate of 1.33 per month. The recruitment timeline had to be extended by 4 months, to meet the target of 16 randomized participants. Staggered recruitment was the most successful strategy. We found that following up with individuals who missed initial appointments prior to study enrollment led to decreased adherence. CONCLUSION: It is feasible to recruit and retain post-stroke participants for an intense intervention study. TRIAL REGISTRATION: NCT02277028.