The Cormatrix Cor™ Patch for Epicardial Infarct Repair
Vishnu Vasanthan, Matteo Biglioli, Ali Fatehi Hassanabad, Jameson A. Dundas, Robert G. Matheny, Paul W.M. Fedak
Abstract
Contemporary management of ischemic heart disease lacks strategies to directly access the heart and promote reparative cellular mechanisms to improve postinfarct cardiac remodeling. Epicardial infarct repair (EIR) is an emerging technique whereby bioactive materials are sewn over ischemic areas of the heart at the time of surgical revascularization to promote adaptive cardiac repair. The CorMatrix Cor™ PATCH (CorMatrix Cardiovascular Inc., GA, USA) is an acellular bioactive material compatible with EIR. Herein, we review current preclinical and clinical data for the CorMatrix Cor PATCH and its use in EIR.
Topics & Concepts
MedicineCardiologyMyocardial infarctionInternal medicineRevascularizationTissue Engineering and Regenerative MedicineElectrospun Nanofibers in Biomedical ApplicationsCardiac Structural Anomalies and Repair