Comprehensive Genomic Investigation of Tigecycline Resistance Gene <i>tet</i> (X4)-Bearing Strains Expanding among Different Settings
Ruichao Li, Yan Li, Kai Peng, Yi Yin, Yuan Liu, Tao He, Li Bai, Zhiqiang Wang
Abstract
Tigecycline was considered the last-line drug against serious infections caused by multidrug-resistant Gram-negative bacteria. However, the plasmid-mediated tigecycline resistance gene tet (X) has been widely reported in different sources of Enterobacterales and Acinetobacter in China.
Topics & Concepts
TigecyclineBiologyGeneticsGeneResistance (ecology)Bearing (navigation)BiotechnologyAntibioticsGeographyEcologyCartographyAntibiotic Resistance in BacteriaPharmaceutical and Antibiotic Environmental ImpactsBacteriophages and microbial interactions