Artemisinin inhibits NRas palmitoylation by targeting the protein acyltransferase ZDHHC6
Nan Qiu, Daniel Abegg, Mara Guidi, Kerry Gilmore, Peter H. Seeberger, Alexander Adibekian
Topics & Concepts
PalmitoylationNeuroblastoma RAS viral oncogene homologCancer researchCell biologyArtemisininAcyltransferaseChemistryBiologyBiochemistryEnzymeGeneMutationKRASImmunologyCysteinePlasmodium falciparumMalariaBiochemical and Molecular ResearchUbiquitin and proteasome pathwaysProtein Kinase Regulation and GTPase Signaling