Desialylation of O‐glycans activates von Willebrand factor by destabilizing its autoinhibitory module
Kayleigh M. Voos, Wenpeng Cao, Nicholas A. Arce, Emily R. Legan, Yingchun Wang, Asif Shajahan, Parastoo Azadi, Pete Lollar, Xiao Hui Zhang, Renhao Li
Topics & Concepts
Von Willebrand factorGlycanChemistryCell biologyPlateletMedicineBiochemistryBiologyInternal medicineGlycoproteinGlycosylation and Glycoproteins ResearchProteoglycans and glycosaminoglycans researchPlatelet Disorders and Treatments