Tunable rigidity of PLGA shell-lipid core nanoparticles for enhanced pulmonary siRNA delivery in 2D and 3D lung cancer cell models
Hezhi Wang, Ye Yuan, Qin Lu, Mengmeng Yue, Jingwen Xue, Zhixiang Cui, Xuanguang Zhan, Jiayi Gai, Xin Zhang, Jian Guan, Shirui Mao
Topics & Concepts
PLGAA549 cellBiophysicsTransfectionChemistryLipofectamineInternalizationMaterials scienceNanotechnologyNanoparticleCellBiologyBiochemistryRecombinant DNAVector (molecular biology)GeneRNA Interference and Gene DeliveryInhalation and Respiratory Drug DeliveryLipid Membrane Structure and Behavior