Hepatocyte-specific deletion of XBP1 sensitizes mice to liver injury through hyperactivation of IRE1α
Caroline C. Duwaerts, Kevin Siao, Russell K. Soon, Chris Her, Takao Iwawaki, Kenji Kohno, Aras N. Mattis, Jacquelyn J. Maher
Topics & Concepts
XBP1Unfolded protein responseEndoplasmic reticulumBiologyEndocrinologyInternal medicineCell biologyMedicineRNA splicingBiochemistryRNAGeneEndoplasmic Reticulum Stress and DiseaseRNA regulation and diseaseGenomics, phytochemicals, and oxidative stress