NUCB2 inhibition antagonizes osteosarcoma progression and promotes anti-tumor immunity through inactivating NUCKS1/CXCL8 axis
Renchen Ji, Yuan Wang, Deyue Pan, Jian Han, Y Wang, Shuo Zheng, Wenzhi Zhao, Xiaojie Li, Chuanchun Han, Lu Zhang, Lu Zhang
Topics & Concepts
OsteosarcomaCancer researchTumor microenvironmentBiologyTumor progressionChemokineIn vivoProgrammed cell deathInterleukin 8Cell biologySignal transductionChemistryImmunologyImmune systemCancerInflammationApoptosisBiochemistryTumor cellsBiotechnologyGeneticsUbiquitin and proteasome pathwaysCAR-T cell therapy researchinterferon and immune responses