Recent progress in therapeutic applications of fluorinated five-membered heterocycles and their benzo-fused systems
Ashraf A. Abbas, Thoraya A. Farghaly, Kamal M. Dawood
Abstract
receptor, serotonin receptor, chemokine receptor, prostaglandin-D2 receptor, and PBR inhibition activities. In many cases, the activities of fluorinated azoles were almost equal to or exceeded the potency of reference drugs.
Topics & Concepts
ChemistryCombinatorial chemistryStereochemistryMedicinal chemistryFluorine in Organic ChemistrySynthesis and Reactions of Organic CompoundsSynthesis and Biological Evaluation