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Detection of SARS-CoV-2 by Use of the Cepheid Xpert Xpress SARS-CoV-2 and Roche cobas SARS-CoV-2 Assays

Angelica Moran, Kathleen G. Beavis, Scott Matushek, Carol Ciaglia, Nina Francois, Vera Tešić, Nedra Love

2020Journal of Clinical Microbiology151 citationsDOIOpen Access PDF

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus responsible for a December 2019 outbreak in Wuhan, China, causes a syndrome characterized by fever, cough, and dyspnea progressing to acute respiratory distress syndrome (1). SARS-CoV-2 quickly spread to other countries, with the new coronavirus disease 2019 (COVID-19) declared a pandemic in March 2020 (2–4). Rapid testing for SARS-CoV-2 is important for epidemiological tracking and institution of quarantine procedures (5). The clinical description of COVID-19 continues to evolve; with transmission by asymptomatic individuals reported (6–8), widespread testing is necessary.

Topics & Concepts

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)PandemicVirologyMedicineCoronavirusCoronavirus disease 2019 (COVID-19)Outbreak2019-20 coronavirus outbreakBetacoronavirusAsymptomaticTransmission (telecommunications)DiseaseInfectious disease (medical specialty)Internal medicineElectrical engineeringEngineeringCOVID-19 diagnosis using AICOVID-19 Clinical Research StudiesSARS-CoV-2 detection and testing