Tubulin-Binding 3,5-Bis(styryl)pyrazoles as Lead Compounds for the Treatment of Castration-Resistant Prostate Cancer
Vivian W. Y. Liao, Anuradha Kumari, Rajeshwar Narlawar, Soma Vignarajan, David E. Hibbs, Dulal Panda, Paul W. Groundwater
Topics & Concepts
TubulinLNCaPDU145MicrotubuleVinblastineColchicineDocetaxelPaclitaxelCell cycleChemistryCell growthMicrotubule polymerizationApoptosisCellProstate cancerCell cultureCell divisionPharmacologyBiologyBiochemistryCell biologyCancerMedicineInternal medicineChemotherapyGenetics14-3-3 protein interactionsCancer Treatment and PharmacologyMetal complexes synthesis and properties