Amplification-free detection of HBV DNA mediated by CRISPR-Cas12a using surface-enhanced Raman spectroscopy
Yuwan Du, Shuaifeng Ji, Qingyang Dong, Jiang Wang, Dianpeng Han, Zhixian Gao
Topics & Concepts
Nucleic acidCRISPRTrans-activating crRNAChemistryDNASurface-enhanced Raman spectroscopyNucleic acid quantitationNucleic acid detectionComputational biologyGenome editingBiochemistryRaman spectroscopyBiologyGeneRaman scatteringOpticsPhysicsCRISPR and Genetic EngineeringAdvanced biosensing and bioanalysis techniquesBiosensors and Analytical Detection