Rational design of the carbonyl reductase EbSDR8 for efficient biosynthesis of enantiopure (R)-3-chloro-1-phenyl-1-propanol
Ze-Hui Shao, Bingmei Su, Shengli Yang, Lidan Ye, Hongwei Yu
Topics & Concepts
Enantiopure drugBiocatalysisChemistrySteric effectsSubstrate (aquarium)ReductaseCofactorSolventBiosynthesisStereochemistryPropanolRational designCatalysisCombinatorial chemistryEnzymeOrganic chemistryReaction mechanismEnantioselective synthesisMaterials scienceEthanolBiologyNanotechnologyEcologyEnzyme Catalysis and ImmobilizationMicrobial Metabolic Engineering and BioproductionPharmacogenetics and Drug Metabolism