Reversible redox-responsive <sup>1</sup>H/<sup>19</sup>F MRI molecular probes
Hongming Chen, Xiaoxue Tang, Xuanqing Gong, Dongxia Chen, Ao Li, Chengjie Sun, Hongyu Lin, Jinhao Gao
Abstract
Herein we report a pair of redox-responsive manganese complexes Mn(iii)/(ii)-N,N'-bis(2-hydroxy-4-trifluoromethylbenzyl)ethylenediamine-N,N'-diacetate (HTFBED, L1), which are water soluble and biologically interconvertible, as reversible redox-responsive probes in 1H/19F MRI for detecting and imaging biological redox species, offering a means to access valuable redox information associated with various diseases.
Topics & Concepts
RedoxChemistryPhysicsNuclear magnetic resonanceCrystallographyInorganic chemistryLanthanide and Transition Metal ComplexesElectron Spin Resonance StudiesMagnetism in coordination complexes