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Normal aging induces PD-1-enriched exhausted microglia and A1-like reactive astrocytes in the hypothalamus

Yukari Suda, Toshihisa Nakashima, Hiroaki Matsumoto, Daisuke Sato, Satoshi Nagano, Haruka Mikata, Sara Yoshida, Kenichi Tanaka, Yusuke Hamada, Naoko Kuzumaki, Minoru Narita

2021Biochemical and Biophysical Research Communications28 citationsDOI

Topics & Concepts

MicrogliaHypothalamusSenescenceNeuroinflammationAstrocyteEndocrinologyInternal medicineBiologyNeurogliaNeuroscienceCentral nervous systemInflammationMedicineNeuroinflammation and Neurodegeneration MechanismsTryptophan and brain disordersNeurogenesis and neuroplasticity mechanisms
Normal aging induces PD-1-enriched exhausted microglia and A1-like reactive astrocytes in the hypothalamus | Litcius