METTL3 Promotes Osteogenic Differentiation of Human Periodontal Ligament Stem Cells through IGF2BP1-Mediated Regulation of Runx2 Stability
Xuefei Sun, Xiujiao Meng, Y. Piao, Shaojie Dong, Qianqian Dong
Abstract
A on regulation of osteogenic differentiation in hPDLSCs and served novel therapeutic approaches in vital periodontitis therapy.
Topics & Concepts
Periodontal ligament stem cellsRUNX2Gene knockdownCell biologyPeriodontal fiberStem cellCellular differentiationTranscription factorChemistryBiologyCell cultureMedicineDentistryAlkaline phosphataseGeneticsBiochemistryGeneEnzymeRNA modifications and cancerCancer-related gene regulationCancer-related molecular mechanisms research