Impact of presymptomatic COVID-19 on vascular and skeletal muscle function: a case study
Joel D. Trinity, Jesse C. Craig, Caitlin C. Fermoyle, Alec I. McKenzie, Matthew T. Lewis, Soung Hun Park, Matthew T. Rondina, Russell S. Richardson
Abstract
This unique case study details the impact of SARS-CoV-2 infection on vascular and skeletal muscle function in a young predominantly presymptomatic woman. Prior to COVID-19 diagnosis, substantial reductions in vascular, skeletal muscle, and mitochondrial function were observed along with an elevation in IL-10. This integrative case study indicates that the presymptomatic impact of COVID-19 is widespread and may help elucidate the acute and long-term sequelae of this disease.
Topics & Concepts
Skeletal muscleCoronavirus disease 2019 (COVID-19)MedicineInternal medicineDiseaseInfectious disease (medical specialty)Long-Term Effects of COVID-19Cardiovascular Disease and AdiposityThermoregulation and physiological responses