Polygenic Risk Scores for Breast Cancer—Can They Deliver on the Promise of Precision Medicine?

Abstract

Cong Liu, PhD; Nur Zeinomar, PhD; Wendy K. Chung, MD, PhD; Krzysztof Kiryluk, MD; Ali G. Gharavi, MD; George Hripcsak, MD; Katherine D. Crew, MD; Ning Shang, PhD; Atlas Khan, PhD; David Fasel, BS; Teri A. Manolio, MD, PhD; Gail P. Jarvik, MD, PhD; Robb Rowley, MD; Ann E. Justice, PhD; Alanna K. Rahm, PhD; Stephanie M. Fullerton, DPhil; Jordan W. Smoller, MD, ScD; Eric B. Larson, MD; Paul K. Crane, MD; Ozan Dikilitas, MD; Georgia L. Wiesner, MD; Alexander G. Bick, MD, PhD; Mary Beth Terry, PhD; Chunhua Weng, PhD

Topics & Concepts