Hybrid Carbon Dot Assembly as a Reactive Oxygen Species Nanogenerator for Ultrasound-Assisted Tumor Ablation
Deblin Jana, Dongdong Wang, Praveenbalaji Rajendran, Anivind Kaur Bindra, Yi Guo, Jiawei Liu, Manojit Pramanik, Yanli Zhao
Abstract
results indicate that CMIR-CDa has a high potency as an ROS nanogenerator under US irradiation, even at a low concentration. The present study offers an approach for engineering hybrid CDs in a bioinspired way for intratumoral ROS augmentation in response to deep tissue penetrable external stimuli.
Topics & Concepts
Reactive oxygen speciesSinglet oxygenEthylene glycolBiocompatibilityFluorescenceIn vivoPhotochemistryNanoparticleChemistryFluorescence-lifetime imaging microscopyHydroxyl radicalOxygenBiophysicsSuperoxideNanotechnologyMaterials scienceRadicalBiochemistryOrganic chemistryEnzymeBiologyBiotechnologyPhysicsQuantum mechanicsNanoplatforms for cancer theranosticsCarbon and Quantum Dots ApplicationsAdvanced Nanomaterials in Catalysis