An antioxidant nanodrug protects against hepatic ischemia–reperfusion injury by attenuating oxidative stress and inflammation
Shuai Zhang, Yue Cao, Bo Xu, Hao Zhang, Songtao Zhang, Jian Sun, Ying Tang, Yinghui Wang
Abstract
production. By exploring the underlying mechanisms of the CM NCs in the treatment of hepatic IRI, we suggest that the CM NCs with ROS scavenging and inflammation regulation capacity show clinical potential for hepatic IRI management and provide new perspectives in the treatment of other oxidative-stress-related diseases.
Topics & Concepts
Oxidative stressInflammationReperfusion injuryBiocompatibilityIschemiaAntioxidantPharmacologyMedicineMaterials scienceImmunologyChemistryInternal medicineBiochemistryMetallurgyAdvanced Nanomaterials in CatalysisSulfur Compounds in BiologyOrgan Transplantation Techniques and Outcomes