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HIF-1-dependent heme synthesis promotes gemcitabine resistance in human non-small cell lung cancers via enhanced ABCB6 expression

Lisha Xiang, Yongsheng Wang, Jie Lan, Feifei Na, Shuang Wu, Yuzhu Gong, Hanjian Du, Bin Shao, Ganfeng Xie

2022Cellular and Molecular Life Sciences23 citationsDOIOpen Access PDF

Topics & Concepts

GemcitabineCancer researchHemeChemistryApoptosisLung cancerBiologyCancerOncologyMedicineBiochemistryEnzymeGeneticsPancreatic and Hepatic Oncology ResearchCancer, Hypoxia, and MetabolismHepatocellular Carcinoma Treatment and Prognosis
HIF-1-dependent heme synthesis promotes gemcitabine resistance in human non-small cell lung cancers via enhanced ABCB6 expression | Litcius