Hybrid aptamer-molecularly imprinted polymer (AptaMIP) nanoparticles selective for the antibiotic moxifloxacin
Mark V. Sullivan, Francia Allabush, David H. J. Bunka, Arron Tolley, Paula M. Mendes, James H. R. Tucker, Nicholas W. Turner
Abstract
A polymerisable aptamer incorporated into Molecularly Imprinted Polymer nanoparticles (MIPs) creates a hybrid “best-of-both-worlds” approach which outperforms individual constituent components.
Topics & Concepts
Molecularly imprinted polymerAptamerMoxifloxacinNanoparticlePolymerMolecular imprintingChemistryNanotechnologyCombinatorial chemistryMaterials scienceAntibioticsSelectivityOrganic chemistryMolecular biologyBiochemistryBiologyCatalysisAnalytical chemistry methods developmentAdvanced biosensing and bioanalysis techniquesAntibiotics Pharmacokinetics and Efficacy