Evaluating the effect of synthesis, isolation, and characterisation variables on reported particle size and dispersity of drug loaded PLGA nanoparticles
Bruna Cambraia Garms, Hamish Poli, Darcy Baggley, Felicity Y. Han, Andrew K. Whittaker, A. Anitha, Lisbeth Grøndahl
Abstract
This work provides advice for PLGA-based nanoparticle fabrication and drug encapsulation quantification as well as the minimum required information to be reported allowing reproducibility.
Topics & Concepts
DispersityPLGANanoparticleParticle sizeNanotechnologyReproducibilityMaterials scienceDrugFabricationChemistryChemical engineeringChromatographyPharmacologyMedicinePolymer chemistryEngineeringPathologyAlternative medicineAdvanced Drug Delivery SystemsNanoparticle-Based Drug DeliveryProteins in Food Systems