The case of methotrexate and the lung: Dr Jekyll and Mr Hyde
Vincent Cottin, Elisabeth Bendstrup, Philippe Bonniaud, Mouhamad Nasser, Paolo Spagnolo, Claudia Valenzuela, Martin Kolb
Abstract
<b>Methotrexate can induce subacute hypersensitivity pneumonitis, a potentially lethal condition that should lead to drug discontinuation; however, its use does not seem to be associated with increased risk of chronic fibrosing ILD in rheumatoid arthritis</b>https://bit.ly/3sCyjji
Topics & Concepts
MedicineMethotrexateDiscontinuationRheumatoid arthritisHypersensitivity pneumonitisPneumonitisLungDermatologyLung fibrosisInternal medicineImmunologyPulmonary fibrosisInterstitial Lung Diseases and Idiopathic Pulmonary FibrosisRheumatoid Arthritis Research and TherapiesDrug-Induced Adverse Reactions