High-Volume Hemodiafiltration and Cool Hemodialysis Have a Beneficial Effect on Intradialytic Hemodynamics: A Randomized Cross-Over Trial of Four Intermittent Dialysis Strategies
Paul A Rootjes, Sabrine Chaara, Camiel L.M. de Roij van Zuijdewijn, Menso J. Nubé, Gertrude Wijngaarden, Muriël P.C. Grooteman
Abstract
Introduction: Compared to standard hemodialysis (S-HD), postdilution hemodiafiltration (HDF) has been associated with improved survival. Methods: analysis on early-onset IDH was performed as well. Secondary endpoints included intradialytic courses of SBP, diastolic BP (DBP) and mean arterial pressure (MAP). Results: < 0.01). Conclusion: Though C-HD and HV-HDF showed the lowest IDH frequency and the best intradialytic hemodynamic stability, all parameters were most disrupted in S-HD. Therefore, the survival benefit of HV-HDF over S-HD may be partly caused by a more beneficial intradialytic BP profile.
Topics & Concepts
MedicineHemodialysisDialysisBlood pressureHemodynamicsCardiologyInternal medicineClinical endpointBlood volumeRandomized controlled trialAnesthesiaDialysis and Renal Disease ManagementCentral Venous Catheters and HemodialysisAcute Kidney Injury Research