Drug screening identifies aldose reductase as a novel target for treating cisplatin-induced hearing loss
Yaqi Liao, Huanyu Mao, Xianhua Gao, Hailiang Lin, Wenyan Li, Yan Chen, Huawei Li
Topics & Concepts
Aldose reductaseOtotoxicityCisplatinAldose reductase inhibitorPharmacologyPolyol pathwayHair cellBiochemistryChemistryReductaseOxidative stressEnzymeMedicineInternal medicineCochleaChemotherapyAnatomyAldose Reductase and TaurineNeonatal Health and BiochemistryBioactive natural compounds