ROS-mediated MAPK activation aggravates hyperoxia-induced acute lung injury by promoting apoptosis of type II alveolar epithelial cells via the STAT3/miR-21–5p axis
Song Qin, Junya Liu, Xiaoqin Wang, Banghai Feng, Yingcong Ren, Jie Zheng, Kun Yu, Hong Yu, Kang Li, Feng Zhu, Miao Chen, Xiaoyun Fu, Tao Chen, Zhouxiong Xing, Hong Mei
Topics & Concepts
ApoptosisMAPK/ERK pathwayHyperoxiaChemistryCell biologyPhosphorylationSTAT3Reactive oxygen speciesCancer researchBiologyBiochemistryOxygenOrganic chemistryMicroRNA in disease regulationHydrogen's biological and therapeutic effectsRespiratory Support and Mechanisms