Mn<sup>3+</sup>-rich oxide/persistent luminescence nanoparticles achieve light-free generation of singlet oxygen and hydroxyl radicals for responsive imaging and tumor treatment
Dandan Ding, Yushuo Feng, Ruixue Qin, Shi Li, Lei Chen, Jinpeng Jing, Chutong Zhang, Wenjing Sun, Yimin Li, Xiaoyuan Chen, Hongmin Chen
Abstract
and oxygen-independent ·OH in tumors allow for more accurate diagnosis of deep tumors and more efficient inhibition of tumor growth without external activation energy.
Topics & Concepts
Singlet oxygenTumor hypoxiaReactive oxygen speciesChemistryRadicalPhotochemistryBiodistributionPreclinical imagingOxygenMaterials scienceIn vivoIn vitroOrganic chemistryInternal medicineMedicineBiotechnologyBiologyBiochemistryRadiation therapyNanoplatforms for cancer theranosticsLuminescence Properties of Advanced MaterialsLuminescence and Fluorescent Materials