Iron-catalyzed alkyne–carbonyl metathesis for the synthesis of 6,7-dihydro-5<i>H</i>-dibenzo[<i>c</i>,<i>e</i>]azonines
Baitan Chakraborty, Umasish Jana
Abstract
The synthesis of nine-membered rings via iron-catalyzed alkyne–carbonyl methathesis (ACM) is reported. Biaryl substrates containing alkyne and acetal units undergo intramolecular ACM to furnish the unexplored 6,7-dihydro-5 H -dibenzo[ c , e ]azonines.
Topics & Concepts
AlkyneChemistryMetathesisCatalysisIntramolecular forceSalt metathesis reactionAcetalCombinatorial chemistryStereochemistryOrganic chemistryPolymerizationPolymerSynthetic Organic Chemistry MethodsAsymmetric Synthesis and CatalysisAdvanced Synthetic Organic Chemistry