Drug Mimicry: Promiscuous Receptors PXR and AhR, and Microbial Metabolite Interactions in the Intestine
Zdeněk Dvořák, Harry Sokol, Sridhar Mani
Topics & Concepts
Pregnane X receptorAryl hydrocarbon receptorMetaboliteReceptorDrugLigand (biochemistry)Drug discoveryBiologyPharmacologyTranscription factorG protein-coupled receptorChemistryComputational biologyNuclear receptorBiochemistryGenePharmacogenetics and Drug MetabolismInflammatory mediators and NSAID effectsDrug Transport and Resistance Mechanisms