Fluorescent probes for <i>in vitro</i> and <i>in vivo</i> quantification of hydrogen peroxide
Sen Ye, Jun Hu, Qian Angela Zhao, Dan Yang
Abstract
New class of H<sub>2</sub>O<sub>2</sub> probes, <bold>HKPerox-Red</bold> and <bold>HKPerox-Ratio</bold>, were developed for quantitative measurement of H<sub>2</sub>O<sub>2</sub> generated in multiple disease models using bio-imaging, flow cytometry, and <italic>in vitro</italic> assays in an ultra-sensitive and selective manner.
Topics & Concepts
Hydrogen peroxideIn vivoFluorescenceIn vitroChemistryBiophysicsCombinatorial chemistryPhotochemistryBiochemistryBiologyPhysicsGeneticsOpticsSulfur Compounds in BiologyMolecular Sensors and Ion DetectionRedox biology and oxidative stress