Litcius/Paper detail

Modelling the Effectiveness of Epidemic Control Measures in Preventing the Transmission of COVID-19 in Malaysia

Balvinder Singh Gill, Vivek Jason Jayaraj, Sarbhan Singh, Sumarni Mohd Ghazali, Yoon Ling Cheong, Nuur Hafizah Md Iderus, Bala Murali Sundram, Tahir Aris, Hishamshah Mohd Ibrahim, Boon Hao Hong, Jane Labadin

2020International Journal of Environmental Research and Public Health47 citationsDOIOpen Access PDF

Abstract

Malaysia is currently facing an outbreak of COVID-19. We aim to present the first study in Malaysia to report the reproduction numbers and develop a mathematical model forecasting COVID-19 transmission by including isolation, quarantine, and movement control measures. We utilized a susceptible, exposed, infectious, and recovered (SEIR) model by incorporating isolation, quarantine, and movement control order (MCO) taken in Malaysia. The simulations were fitted into the Malaysian COVID-19 active case numbers, allowing approximation of parameters consisting of probability of transmission per contact (β), average number of contacts per day per case (ζ), and proportion of close-contact traced per day (q). The effective reproduction number (Rt) was also determined through this model. Our model calibration estimated that (β), (ζ), and (q) were 0.052, 25 persons, and 0.23, respectively. The (Rt) was estimated to be 1.68. MCO measures reduce the peak number of active COVID-19 cases by 99.1% and reduce (ζ) from 25 (pre-MCO) to 7 (during MCO). The flattening of the epidemic curve was also observed with the implementation of these control measures. We conclude that isolation, quarantine, and MCO measures are essential to break the transmission of COVID-19 in Malaysia.

Topics & Concepts

QuarantineCoronavirus disease 2019 (COVID-19)Basic reproduction numberIsolation (microbiology)Transmission (telecommunications)OutbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Statistics2019-20 coronavirus outbreakPandemicDemographyMathematicsBiologyComputer scienceMedicineVirologyInfectious disease (medical specialty)Environmental healthTelecommunicationsPopulationEcologySociologyMicrobiologyDiseasePathologyCOVID-19 epidemiological studiesCOVID-19 Pandemic ImpactsSARS-CoV-2 and COVID-19 Research