Increased chemotherapy-induced ovarian reserve loss in women with germline BRCA mutations due to oocyte deoxyribonucleic acid double strand break repair deficiency
Kutluk Oktay, Giuliano Bedoschi, Shari Goldfarb, Enes Taylan, Shiny Titus, Glenn E. Palomaki, Tessa Cigler, Mark E. Robson, Maura N. Dickler
Topics & Concepts
Ovarian reserveChemotherapyFertility preservationBRCA mutationOncologyChemotherapy regimenMedicineOvarian cancerCyclophosphamideInternal medicineBreast cancerRegimenGermlineInfertilityCancerCancer researchFertilityBiologyPregnancyGeneticsPopulationGeneEnvironmental healthReproductive Biology and FertilityOvarian cancer diagnosis and treatmentBRCA gene mutations in cancer