Di-(2-ethylhexyl) phthalate triggers DNA methyltransferase 1 expression resulting in elevated CpG-methylation and enrichment of MECP2 in the p21 promoter in vitro
Krishna Ghosh, Biji Chatterjee, Kirankumar Nalla, Bablu Behera, Amit Mukherjee, Santosh R. Kanade
Topics & Concepts
DNA methylationEpigeneticsDNMT1PhthalateCpG siteMethylationBiologyDNA methyltransferaseMolecular biologyCyclin D1MECP2Transcription factorGene silencingRegulation of gene expressionChemistryCancer researchGene expressionCell cycleDNAGeneBiochemistryPhenotypeOrganic chemistryEffects and risks of endocrine disrupting chemicalsMicroplastics and Plastic PollutionEpigenetics and DNA Methylation