A Unifying Bioinspired Synthesis of (−)-Asperaculin A and (−)-Penifulvin D
Ian R. George, Miguel López‐Tena, Anders Sundin, Daniel Strand
Abstract
-photocycloaddition biased by an ether substituent at the aryl α-position. The encumbered tertiary alcohol was installed by cyanation of a ketone intermediate followed by nonaqueous hydrolysis of the resulting delicate cyanohydrin.
Topics & Concepts
ChemistryCyanationSubstituentCyanohydrinKetoneEtherSelectivityArylHydrolysisAlcoholStereochemistryCombinatorial chemistryOrganic chemistryCatalysisAlkylOxidative Organic Chemistry ReactionsCatalysis for Biomass ConversionElectrocatalysts for Energy Conversion