Early Treatment of Prethreshold Retinopathy of Prematurity
Alan D. Penman, Kimberly W. Crowder, William M. Watkins
Abstract
The Early Treatment for Retinopathy of Prematurity (ETROP) study, a randomized, controlled clinical trial, compared peripheral retinal ablation with conventional management (observation and treatment if the eye developed threshold retinopathy of prematurity [ROP]) in infants with unilateral or bilateral high-risk ROP. Early treatment of high-risk prethreshold ROP significantly reduced unfavorable outcomes in both primary and secondary (structural) measures. The results of this study showed that it is possible to identify characteristics of ROP that predict which eyes are most likely to benefit from early peripheral retinal ablation.
Topics & Concepts
Retinopathy of prematurityMedicineRetinalOphthalmologyRandomized controlled trialClinical trialPediatricsSurgeryInternal medicineGestational agePregnancyGeneticsBiologyRetinopathy of Prematurity StudiesNeonatal Respiratory Health ResearchNeonatal Health and Biochemistry