Structure-based screening of novel lichen compounds against SARS Coronavirus main protease (Mpro) as potentials inhibitors of COVID-19
Tanuja Joshi, Priyanka Sharma, Tushar Joshi, Hemlata Pundir, Shalini Mathpal, Subhash Chandra
Topics & Concepts
ProteaseVirtual screeningChemistryCoronavirusCoronavirus disease 2019 (COVID-19)StereochemistryDocking (animal)Drug discoverySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)DrugAntiviral drugCombinatorial chemistryLigand (biochemistry)Molecular dynamicsComputational biologyBiochemistryPharmacologyEnzymeBiologyComputational chemistryInfectious disease (medical specialty)DiseaseMedicineNursingPathologyReceptorLichen and fungal ecology