NQO1 alleviates renal fibrosis by inhibiting the TLR4/NF-κB and TGF-β/Smad signaling pathways in diabetic nephropathy
Duojun Qiu, Shan Song, Ning Chen, Yawei Bian, Chen Yuan, Wei Zhang, Huijun Duan, Yonghong Shi
Topics & Concepts
Proinflammatory cytokineFibrosisSMADDiabetic nephropathyChemistryTLR4InflammationSignal transductionCTGFCancer researchEndocrinologyInternal medicineCell biologyBiologyKidneyMedicineReceptorBiochemistryGrowth factorGenomics, phytochemicals, and oxidative stressMicrobial metabolism and enzyme functionNeutrophil, Myeloperoxidase and Oxidative Mechanisms