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Ethical challenges for pediatric liver organoid transplantation

Sarah A. Schneemann, Sarah N. Boers, Johannes J. M. van Delden, Edward E. S. Nieuwenhuis, Sabine A. Fuchs, Annelien L. Bredenoord

2020Science Translational Medicine24 citationsDOIOpen Access PDF

Abstract

Liver organoid transplantation may be a less invasive alternative to liver transplant, but is it ethically acceptable to include children with liver disease in a first-in-human clinical trial of this new intervention?

Topics & Concepts

OrganoidTransplantationLiver transplantationMedicinePathologyBiologyNeuroscienceInternal medicineEthics and Legal Issues in Pediatric HealthcareOrgan Transplantation Techniques and OutcomesLiver physiology and pathology
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