Conserved Epigenetic Regulatory Logic Infers Genes Governing Cell Identity
Woo Jun Shim, Enakshi Sinniah, Jun Xu, Burcu Vitrinel, Michael Alexanian, Gaia Andreoletti, Sophie Shen, Yuliangzi Sun, Brad Balderson, Carles A. Boix, Guangdun Peng, Naihe Jing, Yuliang Wang, Manolis Kellis, Patrick Tam, Aaron Smith, Michael Piper, Lionel Christiaen, Quan Nguyen, Mikael Bodén, Nathan J. Palpant
Topics & Concepts
BiologyComputational biologyEpigeneticsInduced pluripotent stem cellGene regulatory networkCellular differentiationGeneCRISPRRegulation of gene expressionGeneticsTranscriptomeGenomeCell typeCellEmbryonic stem cellGene expressionSingle-cell and spatial transcriptomicsCRISPR and Genetic EngineeringGenomics and Chromatin Dynamics