Fumonisin B1 induces nephrotoxicity via autophagy mediated by mTORC1 instead of mTORC2 in human renal tubule epithelial cells
Lili Hou, Xin Yuan, Guannan Le, Ziman Lin, Fang Gan, Haolei Li, Kehe Huang
Topics & Concepts
mTORC1AutophagyPI3K/AKT/mTOR pathwaymTORC2Fumonisin B1ChemistryProtein kinase BViability assayCell biologyP70-S6 Kinase 1NephrotoxicityCancer researchApoptosisBiochemistryBiologyKidneyEndocrinologyMycotoxinFood scienceMycotoxins in Agriculture and FoodSelenium in Biological SystemsTannin, Tannase and Anticancer Activities