Biological evaluation of mitochondria targeting small molecules as potent anticancer drugs
Shuhua Luo, Xin Dang, Juntao Wang, Yuan Chang, Yixin Hu, Shuwen Lei, Yang Zhang, Dan Lü, Faqin Jiang, Lei Fu
Topics & Concepts
HeLaMitochondrionApoptosisCancer cellDoxorubicinIntracellularChemistryMitochondrial permeability transition poreCancer researchReactive oxygen speciesInner mitochondrial membranePharmacologyCell biologyCancerBiochemistryCellProgrammed cell deathBiologyChemotherapyGeneticsMitochondrial Function and PathologyATP Synthase and ATPases ResearchCancer, Hypoxia, and Metabolism