Discovery, evaluation and mechanism study of WDR5-targeted small molecular inhibitors for neuroblastoma
Qilei Han, Xiang-lei Zhang, Pengxuan Ren, Lianghe Mei, Weihong Lin, Lin Wang, Yu Cao, Kai Li, Fang Bai
Topics & Concepts
NeuroblastomaHEK 293 cellsCell cultureTranscription factorCancer researchGeneBinding siteBiologyCell growthActive siteChemistryCell biologyMolecular biologyGeneticsBiochemistryEnzymeNeuroblastoma Research and TreatmentsSignaling Pathways in DiseaseProtein Degradation and Inhibitors