Neoantigen-specific CD4+ T cells in human melanoma have diverse differentiation states and correlate with CD8+ T cell, macrophage, and B cell function
Joshua Veatch, Sylvia M. Lee, Carolyn Shasha, Naina Singhi, Julia Szeto, Ata S. Moshiri, Teresa S. Kim, Kimberly S. Smythe, Paul Kong, Matthew Fitzgibbon, Brenda L. Jesernig, Shailender Bhatia, Scott S. Tykodi, Evan Hall, David R. Byrd, John A. Thompson, Venu G. Pillarisetty, Thomas Duhen, A. McGarry Houghton, Evan W. Newell, Raphaël Gottardo, Stanley R. Riddell
Topics & Concepts
BiologyCytotoxic T cellCD8Cancer researchTumor microenvironmentInterleukin 21T cellMelanomaImmunologyImmune systemIn vitroGeneticsCancer Immunotherapy and BiomarkersImmunotherapy and Immune ResponsesCAR-T cell therapy research